abstract：AIMS:The impact on mortality outcomes of beta-blockers and calcium blockers in post-myocardial infarction (MI) has been suggested to be related to resting heart rate (HR) reduction. A meta-regression of randomized clinical trials was carried out to assess this relationship using weighted meta-regression of logarithm of...

journal_title：European heart journal

authors： Cucherat M

更新日期：2007-12-01 00:00:00

abstract：AIMS:Hypertrophic cardiomyopathy (HCM) is a disease with marked regional differences in wall thickness. However, the relation between myocardial function and wall thickness has not been well studied. Ultrasonic strain rate (SR) imaging makes it possible to study the regional myocardial deformation. We investigated whet...

journal_title：European heart journal

authors： Ganame J,Mertens L,Eidem BW,Claus P,D'hooge J,Havemann LM,McMahon CJ,Elayda MA,Vaughn WK,Towbin JA,Ayres NA,Pignatelli RH

更新日期：2007-12-01 00:00:00

abstract：AIMS:To determine the impact of surgical myectomy on ventricular arrhythmias in obstructive hypertrophic cardiomyopathy (HCM). Left ventricular outflow tract obstruction (LVOTO) correlates with adverse outcomes, including sudden cardiac death (SCD) in patients with HCM. Surgical myectomy is the primary treatment strate...

journal_title：European heart journal

authors： McLeod CJ,Ommen SR,Ackerman MJ,Weivoda PL,Shen WK,Dearani JA,Schaff HV,Tajik AJ,Gersh BJ

更新日期：2007-11-01 00:00:00

abstract：AIMS:In this study, we compared the clinical outcomes of elderly patients with unprotected left main coronary artery (ULMCA) stenosis treated with either coronary artery bypass grafting (CABG) or drug-eluting stent (DES). METHODS AND RESULTS:From January 2003 to April 2006, 259 patients with ULMCA stenosis and age > o...

journal_title：European heart journal

authors： Palmerini T,Barlocco F,Santarelli A,Bacchi-Reggiani L,Savini C,Baldini E,Alessi L,Ruffini M,Di Credico G,Piovaccari G,Di Bartolomeo R,Marzocchi A,Branzi A,De Servi S

更新日期：2007-11-01 00:00:00

abstract：:Atrial fibrillation (AF) and chronic heart failure (CHF) are two major and even growing cardiovascular conditions that often coexist. However, few data are available to guide treatment of AF in patients with CHF. This review summarizes current literature concerning the following topics: (i) prognostic relevance of AF ...

journal_title：European heart journal

authors： Neuberger HR,Mewis C,van Veldhuisen DJ,Schotten U,van Gelder IC,Allessie MA,Böhm M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess the independent contribution of left bundle branch block (LBBB) on long-term mortality in a large cohort with symptomatic heart failure (HF) requiring hospitalization. METHODS AND RESULTS:We studied a prospective cohort of 21 685 cases of symptomatic HF requiring hosp...

journal_title：European heart journal

authors： Tabrizi F,Englund A,Rosenqvist M,Wallentin L,Stenestrand U

更新日期：2007-10-01 00:00:00

abstract：AIMS:In mechanical heart valve recipients, low-dose international normalized ratio (INR) self-management of oral anticoagulants can reduce the risk of developing thrombo-embolic events and improve long-term survival compared with INR control by a general practitioner. Here, we present data on the safety of low-dose INR...

journal_title：European heart journal

authors： Koertke H,Zittermann A,Tenderich G,Wagner O,El-Arousy M,Krian A,Ennker J,Taborski U,Klövekorn WP,Moosdorf R,Saggau W,Koerfer R

更新日期：2007-10-01 00:00:00

abstract：AIMS:Recent studies suggest an association between acute inflammation and deterioration of arterial function. The effect of acute inflammation on endothelial function and the role of treatment with statins have not been investigated in subjects with dyslipidaemia. METHODS AND RESULTS:In this randomized, placebo-contro...

journal_title：European heart journal

authors： Vlachopoulos C,Aznaouridis K,Dagre A,Vasiliadou C,Masoura C,Stefanadi E,Skoumas J,Pitsavos C,Stefanadis C

更新日期：2007-09-01 00:00:00

abstract：AIM:To examine the association of left ventricular hypertrophy (LVH) on admission electrocardiography with adverse outcomes in acute coronary syndrome (ACS) patients. METHODS AND RESULTS:A total of 7443 non-ST-elevation ACS patients in Global Utilization of STrategies to Open occluded arteries (GUSTO) IV ACS trial had...

journal_title：European heart journal

authors： Westerhout CM,Lauer MS,James S,Fu Y,Wallentin L,Armstrong PW,GUSTO IV ACS Investigators.

更新日期：2007-09-01 00:00:00

abstract：AIMS:To assess safety, feasibility and short term outcome of pulmonary vein (PV) isolation in paroxysmal atrial fibrillation (AF) with a cryoballoon. METHODS:We consecutively treated 57 patients with a double lumen 23 or 28 mm cryoballoon. The acute results, complications and follow-up over the first three months were...

journal_title：European heart journal

authors： Van Belle Y,Janse P,Rivero-Ayerza MJ,Thornton AS,Jessurun ER,Theuns D,Jordaens L

更新日期：2007-09-01 00:00:00

abstract：AIMS:Brugada syndrome (BS) is an ion channelopathy with the risk of sudden cardiac death. The role of programmed ventricular stimulation (PVS) in risk stratification has been controversially discussed. Therefore, we performed a meta-analysis on the prognostic role of PVS in BS. METHODS AND RESULTS:A Medline search unt...

journal_title：European heart journal

authors： Paul M,Gerss J,Schulze-Bahr E,Wichter T,Vahlhaus C,Wilde AA,Breithardt G,Eckardt L

更新日期：2007-09-01 00:00:00

abstract：AIMS:Patients with atrial fibrillation (AF) present with symptoms of myocardial ischaemia despite exclusion of coronary artery disease. A small vessel disease has been suggested. We quantified myocardial perfusion, perfusion reserve, and coronary vascular resistance (CVR) in AF patients using positron emission tomograp...

journal_title：European heart journal

authors： Range FT,Schäfers M,Acil T,Schäfers KP,Kies P,Paul M,Hermann S,Brisse B,Breithardt G,Schober O,Wichter T

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Emerging evidence suggests that a mildly elevated body mass index (BMI), is related to improved survival and fewer cardiovascular events in patients with coronary artery disease (CAD). We hypothesize that these results are related to the poor diagnostic performance of BMI to detect adiposity, especially in t...

journal_title：European heart journal

authors： Romero-Corral A,Somers VK,Sierra-Johnson J,Jensen MD,Thomas RJ,Squires RW,Allison TG,Korinek J,Lopez-Jimenez F

更新日期：2007-09-01 00:00:00

abstract：AIMS:To estimate the incidence of dementia after the first atrial fibrillation (AF), and its impact on survival in a community-based cohort. METHODS AND RESULTS:Olmsted County, Minnesota adult residents diagnosed with first AF during 1986-2000 were identified, and followed until 2004. The primary outcome was new detec...

journal_title：European heart journal

authors： Miyasaka Y,Barnes ME,Petersen RC,Cha SS,Bailey KR,Gersh BJ,Casaclang-Verzosa G,Abhayaratna WP,Seward JB,Iwasaka T,Tsang TS

更新日期：2007-08-01 00:00:00

abstract：AIMS:Major bleeding after percutaneous coronary intervention (PCI) is an independent risk factor for early and late mortality. We developed and validated a risk score predictive of major bleeding after PCI using the femoral approach. METHODS AND RESULTS:Baseline clinical and procedural variables from two contemporary,...

journal_title：European heart journal

authors： Nikolsky E,Mehran R,Dangas G,Fahy M,Na Y,Pocock SJ,Lincoff AM,Stone GW

更新日期：2007-08-01 00:00:00

abstract：:The reperfusion era has dramatically and irrevocably transformed the management of ST-segment elevation myocardial infarction (STEMI). For the patient treated with fibrinolysis as the initial reperfusion strategy, subsequent options which are the subject of some controversy and the focus of this review are (i) facilit...

journal_title：European heart journal

authors： Kiernan TJ,Ting HH,Gersh BJ

更新日期：2007-07-01 00:00:00

abstract：AIMS:Intravascular ultrasound (IVUS) assesses arterial remodelling by comparing the lesion external elastic membrane (EEM) with the reference segments; however, reference segments are rarely disease-free. The aim was to assess lesion and reference segment remodelling and plaque burden in patients with type-2 diabetes m...

journal_title：European heart journal

authors： Jensen LO,Thayssen P,Mintz GS,Maeng M,Junker A,Galloe A,Christiansen EH,Hoffmann SK,Pedersen KE,Hansen HS,Hansen KN

更新日期：2007-07-01 00:00:00

abstract：AIMS:The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account. METHODS AND RESULTS:A total of 2,151 consecutive patients (76....

journal_title：European heart journal

authors： Montalescot G,Dallongeville J,Van Belle E,Rouanet S,Baulac C,Degrandsart A,Vicaut E,OPERA Investigators.

更新日期：2007-06-01 00:00:00

abstract：AIMS:Patients with myocardial infarction (MI) presenting immediately after symptom onset may be treated less aggressively due to their non-elevated troponin status. We compared the initial treatment and clinical outcomes of patients presenting with evolving MI (EMI) with those presenting with MI. METHODS AND RESULTS:T...

journal_title：European heart journal

authors： Miller CD,Banerjee A,Mahaffey KW,Kontos MC,Fermann G,Pollack CV Jr,Antman E,Aylward P,Goodman SG,Santos R,Ferguson JJ,Califf RM,Hoekstra JW

更新日期：2007-05-01 00:00:00

abstract：AIMS:This study investigated the relationship between right ventricular (RV) structure and function and survival in idiopathic pulmonary arterial hypertension (IPAH). METHODS AND RESULTS:In 64 patients, cardiac magnetic resonance, right heart catheterization, and the six-minute walk test (6MWT) were performed at basel...

journal_title：European heart journal

authors： van Wolferen SA,Marcus JT,Boonstra A,Marques KM,Bronzwaer JG,Spreeuwenberg MD,Postmus PE,Vonk-Noordegraaf A

更新日期：2007-05-01 00:00:00

abstract：AIMS:Obstructive sleep apnoea (OSA) is highly prevalent in patients with chronic heart failure (CHF) and may contribute to CHF progression. We aimed to determine whether treatment of OSA with continuous positive airway pressure (CPAP) would improve subjective and objective measures of heart failure severity in patients...

journal_title：European heart journal

authors： Smith LA,Vennelle M,Gardner RS,McDonagh TA,Denvir MA,Douglas NJ,Newby DE

更新日期：2007-05-01 00:00:00

abstract：:Coronary revascularization procedures by means of percutaneous coronary interventions or coronary artery bypass graft surgeries are performed worldwide daily for the symptomatic treatment of patients with myocardial ischaemia. Nevertheless, angina remains a significant clinical problem. Management of angina recurring ...

journal_title：European heart journal

authors： Abbate A,Biondi-Zoccai GG,Agostoni P,Lipinski MJ,Vetrovec GW

更新日期：2007-05-01 00:00:00

abstract：AIMS:Our objectives were (i) to compare the discriminatory performance of the Thrombolysis in Myocardial Infarction risk score (TIMI RS), Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy risk score (PURSUIT RS), and Global Registry of Acute Cardiac Events risk score (GRAC...

journal_title：European heart journal

authors： Yan AT,Yan RT,Tan M,Casanova A,Labinaz M,Sridhar K,Fitchett DH,Langer A,Goodman SG

更新日期：2007-05-01 00:00:00

abstract：:Antithrombotic therapy and invasive risk stratification in selected high-risk patients have improved outcomes from non-ST-segment elevation acute coronary syndromes (NSTE-ACS), but carry a risk of bleeding and blood transfusion. Although the true incidence of bleeding depends on the population studied (i.e. clinical t...

journal_title：European heart journal

authors： Rao SV,Eikelboom JA,Granger CB,Harrington RA,Califf RM,Bassand JP

更新日期：2007-05-01 00:00:00

abstract：AIMS:Hyponatraemia has been shown to be an independent predictor of mortality in selected patients with heart failure enrolled in clinical trials. The predictive value of hyponatraemia has not been evaluated in unselected patients hospitalized with heart failure. METHODS AND RESULTS:OPTIMIZE-HF is a registry and perfo...

journal_title：European heart journal

authors： Gheorghiade M,Abraham WT,Albert NM,Gattis Stough W,Greenberg BH,O'Connor CM,She L,Yancy CW,Young J,Fonarow GC,OPTIMIZE-HF Investigators and Coordinators.

更新日期：2007-04-01 00:00:00

abstract：AIMS:Aspirin combined with clopidogrel is the treatment of choice for acute coronary syndromes. Although the maintenance of aspirin until surgery does not affect postoperative bleeding after coronary artery bypass graft (CABG) surgery, the latter may be dramatically increased when clopidogrel is continued over a period...

journal_title：European heart journal

authors： Ouattara A,Bouzguenda H,Le Manach Y,Léger P,Mercadier A,Leprince P,Bonnet N,Montalescot G,Riou B,Coriat P

更新日期：2007-04-01 00:00:00

abstract：AIMS:The objectives of this study were to determine the association of waist circumference (WC) and waist-to-hip ratio (WHR) with the risk of incident cardiovascular disease (CVD) events and to determine whether the strength of association of WC and WHR with CVD risk is different. METHODS AND RESULTS:This meta-regress...

journal_title：European heart journal

authors： de Koning L,Merchant AT,Pogue J,Anand SS

更新日期：2007-04-01 00:00:00

abstract：AIM:Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) has been suggested as an independent predictor of cardiovascular events in epidemiological studies. We sought to evaluate Lp-PLA(2) as a risk factor for future cardiovascular events in patients with acute coronary syndromes (ACS) and to elucidate the relationshi...

journal_title：European heart journal

authors： Oldgren J,James SK,Siegbahn A,Wallentin L

更新日期：2007-03-01 00:00:00

abstract：:In the near future, the practice of cardiology in Europe will be strongly influenced by a complex interplay of epidemiological, social, economical, professional, and technological evolving factors. The present report summarizes the conclusions of an expert conference organized by the European Society of Cardiology to ...

journal_title：European heart journal

authors： Escaned J,Rydén L,Zamorano JL,Poole-Wilson P,Fuster V,Gitt A,Fernández-Avilés F,Scholte Op Reimer W,de Teresa E,Alonso-Pulpón L,Tendera M,European Conference on the Future of Cardiology.

更新日期：2007-03-01 00:00:00

abstract：AIMS:Here, the aim is to assess long-term clinical variation (CV) of N-terminal pro-brain natriuretic peptide (NT-proBNP) in stable chronic heart failure (CHF) patients. The proposed use of NT-proBNP for monitoring of CHF patients will require accurate information about long-term CV of the peptide. METHODS AND RESULTS...

journal_title：European heart journal

authors： Schou M,Gustafsson F,Kjaer A,Hildebrandt PR

更新日期：2007-01-01 00:00:00

abstract：AIMS:Surgery in patients with infective endocarditis (IE) can be elective (upon completion of antibiotic treatment) or urgent (before antibiotic treatment has ended) when the clinical course is unfavourable. However, urgent surgery for left-sided endocarditis is associated with high mortality. The aims of this study we...

journal_title：European heart journal

authors： Revilla A,López J,Vilacosta I,Villacorta E,Rollán MJ,Echevarría JR,Carrascal Y,Di Stefano S,Fulquet E,Rodríguez E,Fiz L,San Román JA

更新日期：2007-01-01 00:00:00

abstract：AIMS:We sought to investigate the effect of adenosine pretreatment on the incidence of myonecrosis after non-urgent percutaneous coronary intervention (PCI). METHODS AND RESULTS:This was a prospective, randomized, open-label study. Patients who were scheduled for non-urgent PCI in de novo native coronary arteries were...

journal_title：European heart journal

authors： Lee CH,Low A,Tai BC,Co M,Chan MY,Lim J,Lim YT,Tan HC

更新日期：2007-01-01 00:00:00

abstract：AIMS:Experimental and clinical studies indicate that tea exerts protection against cardiovascular diseases. However, a question of much debate is whether addition of milk modifies the biological activities of tea. We studied the vascular effects of tea, with or without milk, in humans and elucidated the impact of indiv...

journal_title：European heart journal

authors： Lorenz M,Jochmann N,von Krosigk A,Martus P,Baumann G,Stangl K,Stangl V

更新日期：2007-01-01 00:00:00

abstract：:Severe primary mitral regurgitation (MR) has a poor outcome if left uncorrected. Successful mitral valve repair has the unique potential to restore normal life expectancy and is superior to valve replacement. Despite this, mitral repair is performed relatively infrequently and many patients with potentially reparable ...

journal_title：European heart journal

authors： Ray S,Chambers J,Gohlke-Baerwolf C,Bridgewater B

更新日期：2006-12-01 00:00:00

abstract：AIMS:Elevated blood pressure (EBP) is the most prevalent and potentially modifiable risk factor for AF, yet little is known of its atrial effects. We aimed to characterize the atrial electrical and structural changes in a chronic ovine model of EBP after prenatal corticosteroid exposure. METHODS AND RESULTS:Twelve she...

journal_title：European heart journal

authors： Kistler PM,Sanders P,Dodic M,Spence SJ,Samuel CS,Zhao C,Charles JA,Edwards GA,Kalman JM

更新日期：2006-12-01 00:00:00

abstract：AIMS:We sought to assess the effect of clopidogrel on clinical events 1 year after discharge in survivors of ST-elevation myocardial infarction (STEMI) in clinical practice. METHODS AND RESULTS:We analysed data of consecutive survivors of acute STEMI and either concomitant therapy with aspirin or aspirin plus clopidog...

journal_title：European heart journal

authors： Zeymer U,Gitt AK,Jünger C,Heer T,Wienbergen H,Koeth O,Bauer T,Mark B,Zahn R,Gottwik M,Senges J,Acute COronary Syndromes (ACOS) registry investigators.

更新日期：2006-11-01 00:00:00

abstract：AIMS:To assess the outcome and costs of patients with acute myocardial infarction (AMI) after initial admission to hospitals with or without catheterization facilities in Belgium. METHODS AND RESULTS:From a nationwide hospital register, we retrieved the data of 34 961 patients discharged during 1999-2001 with a princi...

journal_title：European heart journal

authors： Van Brabandt H,Camberlin C,Vrijens F,Parmentier Y,Ramaekers D,Bonneux L

更新日期：2006-11-01 00:00:00

abstract：AIMS:To document the impact of intensive insulin therapy during intensive care on long-term (4 years) outcome of high-risk cardiac surgery patients. METHODS AND RESULTS:In this pre-planned sub-analysis and follow-up study of a large, randomized controlled trial on the effects of intensive insulin therapy during critic...

journal_title：European heart journal

authors： Ingels C,Debaveye Y,Milants I,Buelens E,Peeraer A,Devriendt Y,Vanhoutte T,Van Damme A,Schetz M,Wouters PJ,Van den Berghe G

更新日期：2006-11-01 00:00:00

abstract：AIMS:Evidence is accumulating that inflammation plays a role in the pathophysiology of heart failure. Lipoprotein-associated phospholipase A2 (Lp-PLA2) has pro-inflammatory properties. We investigated whether Lp-PLA2 activity is associated with heart failure. METHODS AND RESULTS:Lp-PLA2 activity was determined in a ra...

journal_title：European heart journal

authors： van Vark LC,Kardys I,Bleumink GS,Knetsch AM,Deckers JW,Hofman A,Stricker BH,Witteman JC

更新日期：2006-10-01 00:00:00

abstract：AIMS:Our study aimed to examine the management of acute coronary syndromes (ACS) in Europe and the Mediterranean basin, and to compare adherence to guidelines with that reported in the first Euro Heart Survey on ACS (EHS-ACS-I), 4 years earlier. METHODS AND RESULTS:In a prospective survey conducted in 2004 (EHS-ACS-II...

journal_title：European heart journal

authors： Mandelzweig L,Battler A,Boyko V,Bueno H,Danchin N,Filippatos G,Gitt A,Hasdai D,Hasin Y,Marrugat J,Van de Werf F,Wallentin L,Behar S,Euro Heart Survey Investigators.

更新日期：2006-10-01 00:00:00